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1

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Harrison, David E., Strong, Randy, Sharp, Zelton Dave, Nelson, James F., Astle, Clinton M., Flurkey, Kevin, Nadon, Nancy L., Wilkinson, J. Erby, Frenkel, Krystyna, Carter, Christy S., Pahor, Marco, Ja

Journal:

Year:

2009

Language:

english

File:

PDF, 447 KB

english, 2009

2

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

Randy Strong, Richard A. Miller, Clinton M. Astle, Robert A. Floyd, Kevin Flurkey, Kenneth L. Hensley, Martin A. Javors, Christiaan Leeuwenburgh, James F. Nelson, Ennio Ongini, Nancy L. Nad

Journal:

Year:

2008

Language:

english

File:

PDF, 296 KB

english, 2008

3

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

Strong, Randy, Miller, Richard A., Antebi, Adam, Astle, Clinton M., Bogue, Molly, Denzel, Martin S., Fernandez, Elizabeth, Flurkey, Kevin, Hamilton, Karyn L., Lamming, Dudley W., Javors, Martin A., de

Journal:

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

4

Assessing permanent damage to primitive hematopoietic stem cells after chemotherapy using the competitive repopulation assay

Renee V. Gardner, Charles Lerner, Clinton M. Astle, David E. Harrison

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 647 KB

english, 1993

5

An aging Interventions Testing Program: study design and interim report

Richard A. Miller, David E. Harrison, Clinton M. Astle, Robert A. Floyd, Kevin Flurkey, Kenneth L. Hensley, Martin A. Javors, Christiaan Leeuwenburgh, James F. Nelson, Ennio Ongini, Nancy L. Nadon, Hu

Journal:

Year:

2007

Language:

english

File:

PDF, 342 KB

english, 2007

6

Heterozygous Kit Mutants with Little or No Apparent Anemia Exhibit Large Defects in Overall Hematopoietic Stem Cell Function

Yashoda Sharma, Clinton M. Astle, David E. Harrison

Journal:

Experimental Hematology

Year:

2007

Language:

english

File:

PDF, 695 KB

english, 2007

7

Characterization of a hematopoietic stem cell with engraftment advantage

Jichun Chen, Clinton M. Astle, David E. Harrison

Journal:

Experimental Hematology

Year:

2000

Language:

english

File:

PDF, 14 KB

english, 2000

8

Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction

Jichun Chen, Clinton M Astle, David E Harrison

Journal:

Experimental Hematology

Year:

2003

Language:

english

File:

PDF, 247 KB

english, 2003

9

Development and aging of primitive hematopoietic stem cells in BALB/cBy mice

Jichun Chen, Clinton M Astle, David E Harrison

Journal:

Experimental Hematology

Year:

1999

Language:

english

File:

PDF, 262 KB

english, 1999

10

Genetic regulation of primitive hematopoietic stem cell senescence

Jichun Chen, Clinton M Astle, David E Harrison

Journal:

Experimental Hematology

Year:

2000

Language:

english

File:

PDF, 96 KB

english, 2000

11

Mitogen synergism in low-responding CBA/CaJ mice

Clinton M. Astle, David E. Harrison

Journal:

Cellular Immunology

Year:

1976

Language:

english

File:

PDF, 323 KB

english, 1976

12

[Part 1: Biological Sciences] || Effects of Food Restriction on Aging: Separation of Food Intake and Adiposity

David E. Harrison, Jonathan R. Archer and Clinton M. Astle

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 861 KB

english, 1984

13

Number and Continuous Proliferative Pattern of Transplanted Primitive Immunohematopoietic Stem Cells

David E. Harrison, Clinton M. Astle and Charles Lerner

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 793 KB

english, 1988

14

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

Harrison, David E., Strong, Randy, Allison, David B., Ames, Bruce N., Astle, Clinton M., Atamna, Hani, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin A., Nadon, Nancy L., Nelson, James F., Pletc

Journal:

Year:

2014

Language:

english

File:

PDF, 1.03 MB

english, 2014

15

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Miller, Richard A., Harrison, David E., Astle, Clinton M., Fernandez, Elizabeth, Flurkey, Kevin, Han, Melissa, Javors, Martin A., Li, Xinna, Nadon, Nancy L., Nelson, James F., Pletcher, Scott, Salmon,

Journal:

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

16

Regulation of Selenoproteins and Methionine Sulfoxide Reductases A and B1 by Age, Calorie Restriction, and Dietary Selenium in Mice

Novoselov, Sergey V., Kim, Hwa-Young, Hua, Deame, Lee, Byung Cheon, Astle, Clinton M., Harrison, David E., Friguet, Bertrand, Moustafa, Mohamed E., Carlson, Bradley A., Hatfield, Dolph L., Gladyshev,

Journal:

Antioxidants & Redox Signaling

Year:

2010

Language:

english

File:

PDF, 8.01 MB

english, 2010

17

Genetically diverse mice are novel and valuable models of age-associated susceptibility toMycobacterium tuberculosis

Harrison, David E, Astle, Clinton M, Niazi, M, Major, Samuel, Beamer, Gillian L

Journal:

Immunity & Ageing

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

18

Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

Lamming, Dudley W., Ye, Lan, Astle, Clinton M., Baur, Joseph A., Sabatini, David M., Harrison, David E.

Journal:

Year:

2013

Language:

english

File:

PDF, 219 KB

english, 2013

19

POPULATION OF LYMPHOID TISSUES IN CURED W-ANEMIC MICE BY DONOR CELLS

HARRISON, DAVID E., ASTLE, CLINTON M.

Journal:

Transplantation Journal

Year:

1976

File:

PDF, 363 KB

1976

20

Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice

Thompson, Airlia C. S., Bruss, Matthew D., Price, John C., Khambatta, Cyrus F., Holmes, William E., Colangelo, Marc, Dalidd, Marcy, Roberts, Lindsay S., Astle, Clinton M., Harrison, David E., Hellerst

Journal:

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

21

Maximum Life Spans in Mice are Extended by Wild Strain Alleles

Klebanov, Simon, Astle, Clinton M., Roderick, Thomas H., Flurkey, Kevin, Archer, Jonathan R., Chen, Jichun

Journal:

Experimental Biology and Medicine

Year:

2001

Language:

english

File:

PDF, 632 KB

english, 2001

22

Short- and Long-Term Multilineage Repopulating Hematopoietic Stem Cells in Late Fetal and Newborn Mice: Models for Human Umbilical Cord Blood

Harrison, David E., Astle, Clinton M.

Journal:

Year:

1997

File:

PDF, 198 KB

1997

23

Primitive hematopoietic stem cell function in vivo is uniquely high in the CXB-12 mouse strain

Chen, Jichun, Astle, Clinton M., MuÌller-Sieburg, Christa E., Harrison, David E.

Journal:

Year:

2000

File:

PDF, 221 KB

2000